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Important: This site presents data from the FDA Adverse Event Reporting System (FAERS). A report does not mean the drug caused the event. Full disclaimer.

Therapeutic product effect decreased: Which Medications Cause It? (40,797 Reports Across 911 Drugs)

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Therapeutic product effect decreased has been reported as an adverse event with 911 different drugs in the FDA's FAERS database, with 40,797 total reports. 1,641 of these reports resulted in death.The drugs most commonly associated with Therapeutic product effect decreased are ADALIMUMAB, METHOTREXATE, and ETANERCEPT.

40,797
Total Reports
911
Drugs Involved
1,641
Deaths
6,297
Hospitalizations
52.2 yrs
Average Patient Age
69.0% / 31.0%
Female / Male

Which Drugs Cause Therapeutic product effect decreased Most Often?

Drug Reports % of Drug Reports Deaths Hosp. Life-Threat.
ADALIMUMAB 11,058 2.2% 941 3,138 1,283
METHOTREXATE 8,952 3.5% 1,020 2,730 1,372
ETANERCEPT 8,819 2.5% 758 2,261 1,073
ABATACEPT 7,256 6.3% 900 2,465 1,314
TOCILIZUMAB 7,208 7.3% 1,033 2,462 1,308
LEFLUNOMIDE 7,025 12.4% 1,044 2,439 1,304
HYDROXYCHLOROQUINE 6,450 9.7% 953 2,286 1,239
INFLIXIMAB 6,401 4.6% 962 2,335 1,284
RITUXIMAB 6,281 3.5% 1,069 2,510 1,279
GOLIMUMAB 5,478 7.9% 911 1,872 1,179
SULFASALAZINE 5,386 13.4% 939 2,120 1,245
CERTOLIZUMAB PEGOL 5,352 5.4% 876 1,712 1,133
TOFACITINIB 4,934 3.2% 895 1,721 1,177
PREDNISONE 4,408 2.8% 960 1,840 1,262
ALENDRONATE 3,585 12.9% 983 1,732 1,230
FOLIC ACID 3,330 14.6% 973 1,516 1,179
CETIRIZINE 3,292 6.9% 956 1,450 1,186
DESOXIMETASONE 3,273 28.1% 957 1,435 1,179
DICLOFENAC 3,199 3.7% 1,024 1,458 1,222
ACETAMINOPHEN 3,194 2.3% 842 1,194 1,095

View all 911 drugs →

Top 3 Drugs Associated With Therapeutic product effect decreased

11,058 reports
8,952 reports
8,819 reports

Related Side Effects

Drug ineffective (1,049,718) Off label use (762,782) Death (660,423) Fatigue (599,248) Nausea (562,301) Diarrhoea (491,550) Pain (471,975) Headache (460,069) Dyspnoea (409,496) Dizziness (352,922)