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Important: This site presents data from the FDA Adverse Event Reporting System (FAERS). A report does not mean the drug caused the event. Full disclaimer.

Therapeutic response changed: Which Medications Cause It? (4,030 Reports Across 205 Drugs)

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Therapeutic response changed has been reported as an adverse event with 205 different drugs in the FDA's FAERS database, with 4,030 total reports. 63 of these reports resulted in death.The drugs most commonly associated with Therapeutic response changed are TIRZEPATIDE, AMPHETAMINE ASPARTATE\AMPHETAMINE\DEXTROAMPHETAMINE SACCHARATE\DEXTROAMPHETAMINE, and LEVOTHYROXINE.

4,030
Total Reports
205
Drugs Involved
63
Deaths
243
Hospitalizations
49.3 yrs
Average Patient Age
64.9% / 35.1%
Female / Male

Which Drugs Cause Therapeutic response changed Most Often?

Drug Reports % of Drug Reports Deaths Hosp. Life-Threat.
TIRZEPATIDE 550 0.6% 0 0 0
AMPHETAMINE ASPARTATE\AMPHETAMINE\DEXTROAMPHETAMINE SACCHARATE\DEXTROAMPHETAMINE 169 1.1% 0 4 2
LEVOTHYROXINE 124 0.2% 32 1 4
METHYLPHENIDATE 124 0.4% 0 1 3
LAMOTRIGINE 111 0.2% 0 9 3
LISDEXAMFETAMINE DIMESYLATE 104 0.6% 0 2 0
BUPROPION 99 0.3% 0 1 2
NAPROXEN 63 0.1% 0 0 0
PREGABALIN 59 0.1% 0 6 0
CALCIUM OXYBATE\MAGNESIUM OXYBATE\POTASSIUM OXYBATE\SODIUM OXYBATE 55 0.7% 0 9 0
ADALIMUMAB 53 0.0% 1 7 0
DULOXETINE 52 0.1% 0 3 2
ALEVE CAPLET 50 4.0% 0 0 0
BACLOFEN 50 0.2% 0 13 2
LYRICA 49 0.9% 1 0 1
INFLIXIMAB 39 0.0% 2 6 0
BUDESONIDE\FORMOTEROL 38 0.1% 0 4 0
METHOTREXATE 37 0.0% 0 3 0
QUETIAPINE 37 0.1% 0 11 2
CLARITIN CHEWABLE 36 3.5% 0 0 0

View all 205 drugs →

Top 3 Drugs Associated With Therapeutic response changed

550 reports
124 reports

Related Side Effects

Drug ineffective (1,049,718) Off label use (762,782) Death (660,423) Fatigue (599,248) Nausea (562,301) Diarrhoea (491,550) Pain (471,975) Headache (460,069) Dyspnoea (409,496) Dizziness (352,922)