Therapeutic response decreased: Which Medications Cause It? (43,421 Reports Across 992 Drugs)
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Therapeutic response decreased has been reported as an adverse event with 992 different drugs in the FDA's FAERS database, with 43,421 total reports. 1,277 of these reports resulted in death.The drugs most commonly associated with Therapeutic response decreased are DUPILUMAB, ETANERCEPT, and ONABOTULINUMTOXINA.
43,421
Total Reports
992
Drugs Involved
1,277
Deaths
4,947
Hospitalizations
50.2 yrs
Average Patient Age
61.2% / 38.8%
Female / Male
Which Drugs Cause Therapeutic response decreased Most Often?
| Drug | Reports | % of Drug Reports | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| DUPILUMAB | 7,824 | 2.1% | 14 | 225 | 2 |
| ETANERCEPT | 3,460 | 1.0% | 103 | 595 | 203 |
| ONABOTULINUMTOXINA | 2,685 | 5.5% | 0 | 8 | 0 |
| METHOTREXATE | 2,668 | 1.1% | 169 | 709 | 286 |
| INFLIXIMAB | 1,991 | 1.4% | 76 | 648 | 199 |
| RITUXIMAB | 1,728 | 1.0% | 192 | 669 | 330 |
| LEFLUNOMIDE | 1,574 | 2.8% | 120 | 536 | 262 |
| TOCILIZUMAB | 1,512 | 1.5% | 131 | 542 | 257 |
| HYDROXYCHLOROQUINE | 1,485 | 2.2% | 122 | 547 | 252 |
| ADALIMUMAB | 1,357 | 0.3% | 128 | 508 | 242 |
| PREDNISONE | 1,347 | 0.9% | 180 | 513 | 308 |
| ABATACEPT | 1,322 | 1.1% | 105 | 535 | 258 |
| USTEKINUMAB | 1,224 | 1.4% | 102 | 250 | 211 |
| APREMILAST | 1,133 | 0.8% | 98 | 187 | 119 |
| GOLIMUMAB | 1,123 | 1.6% | 110 | 395 | 214 |
| SULFASALAZINE | 1,067 | 2.7% | 110 | 432 | 231 |
| SECUKINUMAB | 862 | 0.6% | 127 | 296 | 227 |
| CYCLOSPORINE | 788 | 1.2% | 36 | 231 | 15 |
| CERTOLIZUMAB PEGOL | 786 | 0.8% | 111 | 304 | 217 |
| FEXOFENADINE | 742 | 3.5% | 1 | 8 | 1 |