Therapy change: Which Medications Cause It? (8,493 Reports Across 393 Drugs)
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Therapy change has been reported as an adverse event with 393 different drugs in the FDA's FAERS database, with 8,493 total reports. 195 of these reports resulted in death.The drugs most commonly associated with Therapy change are MACITENTAN, SELEXIPAG, and EPOPROSTENOL.
8,493
Total Reports
393
Drugs Involved
195
Deaths
2,162
Hospitalizations
54.8 yrs
Average Patient Age
62.1% / 37.9%
Female / Male
Which Drugs Cause Therapy change Most Often?
| Drug | Reports | % of Drug Reports | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| MACITENTAN | 346 | 0.8% | 30 | 303 | 3 |
| SELEXIPAG | 285 | 1.5% | 15 | 265 | 0 |
| EPOPROSTENOL | 237 | 1.8% | 19 | 223 | 3 |
| LENALIDOMIDE | 212 | 0.1% | 2 | 39 | 0 |
| PALBOCICLIB | 204 | 0.2% | 0 | 18 | 0 |
| CAPECITABINE | 200 | 0.3% | 0 | 53 | 0 |
| TREPROSTINIL | 189 | 0.2% | 13 | 167 | 1 |
| GLATIRAMER | 184 | 0.4% | 0 | 23 | 1 |
| AMBRISENTAN | 143 | 0.2% | 4 | 77 | 0 |
| ADALIMUMAB | 139 | 0.0% | 0 | 24 | 0 |
| HUMAN IMMUNOGLOBULIN G | 129 | 0.2% | 9 | 33 | 0 |
| ARIPIPRAZOLE | 128 | 0.2% | 1 | 27 | 3 |
| ETANERCEPT | 110 | 0.0% | 0 | 9 | 1 |
| HUMAN C1-ESTERASE INHIBITOR | 86 | 0.6% | 0 | 41 | 5 |
| TACROLIMUS | 83 | 0.1% | 1 | 40 | 1 |
| ABEMACICLIB | 82 | 0.5% | 0 | 12 | 0 |
| USTEKINUMAB | 80 | 0.1% | 0 | 8 | 0 |
| ABIRATERONE | 78 | 0.2% | 1 | 10 | 1 |
| LAMOTRIGINE | 68 | 0.1% | 0 | 26 | 6 |
| EVEROLIMUS | 67 | 0.2% | 0 | 10 | 0 |