Therapy non-responder: Which Medications Cause It? (38,052 Reports Across 1,168 Drugs)
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Therapy non-responder has been reported as an adverse event with 1,168 different drugs in the FDA's FAERS database, with 38,052 total reports. 3,323 of these reports resulted in death.The drugs most commonly associated with Therapy non-responder are ETANERCEPT, APREMILAST, and METHOTREXATE.
38,052
Total Reports
1,168
Drugs Involved
3,323
Deaths
7,465
Hospitalizations
49.9 yrs
Average Patient Age
60.4% / 39.6%
Female / Male
Which Drugs Cause Therapy non-responder Most Often?
| Drug | Reports | % of Drug Reports | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| ETANERCEPT | 3,472 | 1.0% | 383 | 891 | 566 |
| APREMILAST | 3,360 | 2.5% | 339 | 517 | 389 |
| METHOTREXATE | 2,965 | 1.2% | 633 | 1,245 | 799 |
| RITUXIMAB | 2,731 | 1.5% | 776 | 1,322 | 772 |
| ADALIMUMAB | 2,595 | 0.5% | 475 | 1,135 | 721 |
| PREDNISONE | 2,563 | 1.6% | 613 | 1,159 | 778 |
| TREPROSTINIL | 2,289 | 2.5% | 125 | 620 | 44 |
| INFLIXIMAB | 2,122 | 1.5% | 467 | 1,128 | 713 |
| TOCILIZUMAB | 1,775 | 1.8% | 510 | 1,090 | 727 |
| HYDROXYCHLOROQUINE | 1,699 | 2.6% | 455 | 1,031 | 688 |
| ABATACEPT | 1,615 | 1.4% | 429 | 1,071 | 736 |
| LEFLUNOMIDE | 1,583 | 2.8% | 495 | 997 | 673 |
| SULFASALAZINE | 1,390 | 3.5% | 445 | 982 | 685 |
| DEXAMETHASONE | 1,376 | 1.1% | 287 | 320 | 261 |
| SECUKINUMAB | 1,376 | 0.9% | 497 | 802 | 672 |
| TOFACITINIB | 1,320 | 0.9% | 416 | 801 | 619 |
| MYCOPHENOLATE MOFETIL | 1,275 | 1.7% | 459 | 566 | 439 |
| GOLIMUMAB | 1,256 | 1.8% | 424 | 876 | 600 |
| USTEKINUMAB | 1,189 | 1.4% | 394 | 676 | 570 |
| CYCLOPHOSPHAMIDE | 1,156 | 0.9% | 227 | 242 | 85 |