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Important: This site presents data from the FDA Adverse Event Reporting System (FAERS). A report does not mean the drug caused the event. Full disclaimer.

Thrombotic thrombocytopenic purpura: Which Medications Cause It? (1,996 Reports Across 135 Drugs)

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Thrombotic thrombocytopenic purpura has been reported as an adverse event with 135 different drugs in the FDA's FAERS database, with 1,996 total reports. 368 of these reports resulted in death.The drugs most commonly associated with Thrombotic thrombocytopenic purpura are CLOPIDOGREL BISULFATE, RITUXIMAB, and CYCLOSPORINE.

1,996
Total Reports
135
Drugs Involved
368
Deaths
1,121
Hospitalizations
53.9 yrs
Average Patient Age
52.4% / 47.6%
Female / Male

Which Drugs Cause Thrombotic thrombocytopenic purpura Most Often?

Drug Reports % of Drug Reports Deaths Hosp. Life-Threat.
CLOPIDOGREL BISULFATE 282 0.6% 77 128 36
RITUXIMAB 154 0.1% 11 77 53
CYCLOSPORINE 95 0.1% 10 44 48
CYCLOPHOSPHAMIDE 85 0.1% 4 42 49
TACROLIMUS 82 0.1% 17 37 15
CAPLACIZUMAB-YHDP 63 4.5% 7 26 1
CARFILZOMIB 63 0.3% 16 37 10
METHYLPREDNISOLONE 63 0.1% 3 29 42
ASPIRIN 60 0.1% 13 24 1
QUETIAPINE 58 0.1% 0 49 17
LENALIDOMIDE 57 0.0% 11 37 7
OXALIPLATIN 56 0.1% 16 30 14
BORTEZOMIB 55 0.1% 1 28 40
GEMCITABINE 48 0.2% 19 21 17
CISPLATIN 47 0.1% 17 19 11
DEXAMETHASONE 46 0.0% 9 26 11
MYCOPHENOLATE MOFETIL 46 0.1% 6 26 7
ACETYLCYSTEINE 43 1.8% 3 17 39
PREDNISONE 41 0.0% 2 30 1
ALEMTUZUMAB 38 0.3% 5 29 9

View all 135 drugs →

Top 3 Drugs Associated With Thrombotic thrombocytopenic purpura

282 reports
154 reports
95 reports

Related Side Effects

Drug ineffective (1,049,718) Off label use (762,782) Death (660,423) Fatigue (599,248) Nausea (562,301) Diarrhoea (491,550) Pain (471,975) Headache (460,069) Dyspnoea (409,496) Dizziness (352,922)