Toxic skin eruption: Which Medications Cause It? (6,588 Reports Across 567 Drugs)
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Toxic skin eruption has been reported as an adverse event with 567 different drugs in the FDA's FAERS database, with 6,588 total reports. 206 of these reports resulted in death.The drugs most commonly associated with Toxic skin eruption are SULFAMETHOXAZOLE\TRIMETHOPRIM, ALLOPURINOL, and AMOXICILLIN.
6,588
Total Reports
567
Drugs Involved
206
Deaths
3,264
Hospitalizations
61.3 yrs
Average Patient Age
54.5% / 45.5%
Female / Male
Which Drugs Cause Toxic skin eruption Most Often?
| Drug | Reports | % of Drug Reports | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| SULFAMETHOXAZOLE\TRIMETHOPRIM | 367 | 1.0% | 16 | 235 | 7 |
| ALLOPURINOL | 291 | 1.5% | 16 | 215 | 18 |
| AMOXICILLIN | 291 | 1.0% | 0 | 158 | 3 |
| PIPERACILLIN\TAZOBACTAM | 263 | 1.4% | 2 | 157 | 18 |
| VANCOMYCIN | 250 | 0.7% | 7 | 160 | 14 |
| PANTOPRAZOLE | 233 | 0.3% | 3 | 162 | 0 |
| CLINDAMYCIN | 212 | 1.2% | 8 | 116 | 1 |
| VALACYCLOVIR | 207 | 1.6% | 8 | 117 | 1 |
| CARBOPLATIN | 194 | 0.2% | 3 | 81 | 6 |
| LAMOTRIGINE | 182 | 0.4% | 1 | 128 | 9 |
| LENALIDOMIDE | 174 | 0.1% | 18 | 86 | 19 |
| FUROSEMIDE | 170 | 0.3% | 3 | 118 | 8 |
| LEVOFLOXACIN | 170 | 0.4% | 2 | 104 | 2 |
| DEXAMETHASONE | 169 | 0.1% | 7 | 93 | 8 |
| ESOMEPRAZOLE | 158 | 0.2% | 0 | 107 | 10 |
| PACLITAXEL | 155 | 0.2% | 4 | 55 | 8 |
| AMOXICILLIN\CLAVULANATE | 151 | 1.0% | 9 | 132 | 6 |
| ATORVASTATIN | 138 | 0.2% | 7 | 73 | 8 |
| ENOXAPARIN | 132 | 0.5% | 0 | 83 | 0 |
| MEROPENEM | 131 | 0.9% | 7 | 71 | 12 |