Tumour lysis syndrome: Which Medications Cause It? (6,641 Reports Across 272 Drugs)
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Tumour lysis syndrome has been reported as an adverse event with 272 different drugs in the FDA's FAERS database, with 6,641 total reports. 2,148 of these reports resulted in death.The drugs most commonly associated with Tumour lysis syndrome are VENETOCLAX, RITUXIMAB, and CYCLOPHOSPHAMIDE.
6,641
Total Reports
272
Drugs Involved
2,148
Deaths
3,293
Hospitalizations
58.9 yrs
Average Patient Age
36.4% / 63.6%
Female / Male
Which Drugs Cause Tumour lysis syndrome Most Often?
| Drug | Reports | % of Drug Reports | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| VENETOCLAX | 1,057 | 2.0% | 324 | 499 | 89 |
| RITUXIMAB | 1,056 | 0.6% | 306 | 512 | 175 |
| CYCLOPHOSPHAMIDE | 918 | 0.7% | 291 | 402 | 156 |
| VINCRISTINE | 832 | 1.2% | 246 | 378 | 143 |
| DOXORUBICIN | 803 | 1.0% | 272 | 344 | 131 |
| DEXAMETHASONE | 795 | 0.6% | 219 | 383 | 175 |
| ETOPOSIDE | 553 | 1.1% | 167 | 236 | 107 |
| PREDNISONE | 550 | 0.4% | 177 | 257 | 73 |
| CYTARABINE | 407 | 0.9% | 112 | 191 | 74 |
| CARBOPLATIN | 337 | 0.4% | 97 | 190 | 69 |
| OBINUTUZUMAB | 310 | 2.2% | 46 | 160 | 34 |
| PREDNISOLONE | 309 | 0.4% | 109 | 139 | 43 |
| IBRUTINIB | 300 | 0.4% | 94 | 155 | 31 |
| LENALIDOMIDE | 300 | 0.1% | 98 | 168 | 46 |
| METHOTREXATE | 300 | 0.1% | 90 | 117 | 48 |
| CISPLATIN | 277 | 0.6% | 79 | 120 | 64 |
| BORTEZOMIB | 266 | 0.6% | 62 | 97 | 58 |
| AZACITIDINE | 265 | 1.4% | 119 | 111 | 26 |
| OXALIPLATIN | 247 | 0.4% | 36 | 163 | 52 |
| BENDAMUSTINE | 223 | 1.1% | 53 | 130 | 33 |