Uterine rupture: Which Medications Cause It? (278 Reports Across 15 Drugs)
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Uterine rupture has been reported as an adverse event with 15 different drugs in the FDA's FAERS database, with 278 total reports. 15 of these reports resulted in death.The drugs most commonly associated with Uterine rupture are MISOPROSTOL, DINOPROSTONE, and OXYTOCIN.
278
Total Reports
15
Drugs Involved
15
Deaths
116
Hospitalizations
35.5 yrs
Average Patient Age
100.0% / 0.0%
Female / Male
Which Drugs Cause Uterine rupture Most Often?
| Drug | Reports | % of Drug Reports | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| MISOPROSTOL | 74 | 2.1% | 7 | 32 | 22 |
| DINOPROSTONE | 32 | 4.4% | 1 | 11 | 13 |
| OXYTOCIN | 16 | 1.1% | 1 | 7 | 6 |
| LEVONORGESTREL | 13 | 0.0% | 1 | 7 | 0 |
| MIFEPRISTONE | 11 | 0.2% | 0 | 6 | 5 |
| PREDNISOLONE | 11 | 0.0% | 1 | 8 | 4 |
| ADALIMUMAB | 10 | 0.0% | 0 | 3 | 0 |
| CETIRIZINE | 10 | 0.0% | 0 | 0 | 0 |
| HYDROXYPROGESTERONE CAPROATE | 10 | 0.0% | 1 | 9 | 0 |
| LORATADINE | 10 | 0.0% | 0 | 0 | 0 |
| MONTELUKAST | 10 | 0.0% | 0 | 0 | 0 |
| METHOTREXATE | 8 | 0.0% | 3 | 4 | 0 |
| ASPIRIN | 6 | 0.0% | 0 | 4 | 1 |
| BEVACIZUMAB | 5 | 0.0% | 0 | 3 | 3 |
| COPPER | 5 | 0.0% | 0 | 1 | 1 |