Amide Local Anesthetic [EPC]: Side Effects & Safety Data for 6 Drugs
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Amide Local Anesthetic [EPC] includes 6 drugs with a combined 38,075 adverse event reports in the FDA FAERS database. Compare their safety profiles, side effects, and outcomes below.
6
Drugs in Class
38,075
Combined Reports
All Amide Local Anesthetic [EPC] Drugs Ranked by Reports
| Drug | Brand Name | Reports | Deaths | Hosp. | Death Rate |
|---|---|---|---|---|---|
| LIDOCAINE | Burn Relief | 22,732 | 1,738 | 5,570 | 7.6% |
| BUPIVACAINE | Bupivacaine Hydrochloride | 11,356 | 466 | 2,367 | 4.1% |
| ROPIVACAINE | Ropivacaine Hydrochloride | 2,967 | 150 | 921 | 5.1% |
| MEPIVACAINE | Mepivacaine | 702 | 19 | 183 | 2.7% |
| PRILOCAINE | Citanest Plain | 256 | 2 | 75 | 0.8% |
| LIDOCAINE ANHYDROUS | XYLOCAINE MPF | 62 | 1 | 37 | 1.6% |
Common Side Effects in Amide Local Anesthetic [EPC] Drugs
| Side Effect | Reports | Deaths |
|---|---|---|
| Drug ineffective | 7,193 | 262 |
| Off label use | 3,599 | 273 |
| Product adhesion issue | 3,444 | 1 |
| Product quality issue | 3,264 | 9 |
| Drug ineffective for unapproved indication | 1,825 | 13 |
| Pain | 1,754 | 57 |
| Hypotension | 1,462 | 73 |
| Toxicity to various agents | 1,423 | 577 |
| Drug hypersensitivity | 1,369 | 80 |
| Dyspnoea | 1,288 | 119 |