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Important: This site presents data from the FDA Adverse Event Reporting System (FAERS). A report does not mean the drug caused the event. Full disclaimer.

Centrally-mediated Muscle Relaxation [PE]: Side Effects & Safety Data for 6 Drugs

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Centrally-mediated Muscle Relaxation [PE] includes 6 drugs with a combined 16,471 adverse event reports in the FDA FAERS database. Compare their safety profiles, side effects, and outcomes below.

6
Drugs in Class
16,471
Combined Reports

All Centrally-mediated Muscle Relaxation [PE] Drugs Ranked by Reports

Drug Brand Name Reports Deaths Hosp. Death Rate
CYCLOBENZAPRINE Cyclobenzaprine hydrochloride 9,148 3,862 2,820 42.2%
CARISOPRODOL CARISOPRODOL 2,660 1,332 432 50.1%
METHOCARBAMOL Methocarbamol Tablets, USP, 500 mg 2,201 546 816 24.8%
METAXALONE Metaxalone 1,452 464 175 32.0%
ORPHENADRINE Orphenadrine Citrate 584 121 159 20.7%
CHLORZOXAZONE CHLORZOXAZONE 426 52 126 12.2%

Common Side Effects in Centrally-mediated Muscle Relaxation [PE] Drugs

Side EffectReportsDeaths
Toxicity to various agents 3,018 2,221
Completed suicide 2,482 2,477
Pain 1,810 242
Drug hypersensitivity 1,777 243
Drug ineffective 1,617 242
Drug abuse 1,320 1,030
Overdose 1,224 479
Constipation 1,141 107
Off label use 993 303
Fall 952 25
View detailed side effects for this class → Compare drugs in this class →