Cytochrome P450 1A2 Inducers [MoA]: Side Effects & Safety Data for 5 Drugs
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Cytochrome P450 1A2 Inducers [MoA] includes 5 drugs with a combined 80,154 adverse event reports in the FDA FAERS database. Compare their safety profiles, side effects, and outcomes below.
5
Drugs in Class
80,154
Combined Reports
All Cytochrome P450 1A2 Inducers [MoA] Drugs Ranked by Reports
| Drug | Brand Name | Reports | Deaths | Hosp. | Death Rate |
|---|---|---|---|---|---|
| OSIMERTINIB | TAGRISSO | 27,750 | 12,456 | 5,277 | 44.9% |
| CARBAMAZEPINE | Carbamazepine | 24,577 | 2,156 | 9,608 | 8.8% |
| PHENYTOIN | PHENYTOIN SODIUM | 14,469 | 1,449 | 5,241 | 10.0% |
| RITONAVIR | Norvir | 11,980 | 1,190 | 2,925 | 9.9% |
| FOSPHENYTOIN | CEREBYX | 1,378 | 166 | 646 | 12.0% |
Common Side Effects in Cytochrome P450 1A2 Inducers [MoA] Drugs
| Side Effect | Reports | Deaths |
|---|---|---|
| Death | 11,416 | 11,405 |
| Drug ineffective | 6,672 | 524 |
| Seizure | 4,429 | 169 |
| Toxicity to various agents | 3,594 | 834 |
| Off label use | 3,172 | 396 |
| Foetal exposure during pregnancy | 3,060 | 417 |
| Malignant neoplasm progression | 2,957 | 589 |
| Drug interaction | 2,560 | 176 |
| Rash | 2,375 | 173 |
| Diarrhoea | 2,247 | 235 |