Cytochrome P450 1A2 Inducers [MoA] — Common Side Effects
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| Side Effect | Total Reports | Drugs | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| Death | 11,416 | 5 | 11,405 | 377 | 80 |
| Drug ineffective | 6,672 | 5 | 524 | 2,277 | 677 |
| Seizure | 4,429 | 5 | 169 | 1,306 | 259 |
| Toxicity to various agents | 3,594 | 5 | 834 | 2,199 | 435 |
| Off label use | 3,172 | 5 | 396 | 1,330 | 378 |
| Foetal exposure during pregnancy | 3,060 | 3 | 417 | 318 | 63 |
| Malignant neoplasm progression | 2,957 | 4 | 589 | 370 | 77 |
| Drug interaction | 2,560 | 5 | 176 | 1,211 | 247 |
| Rash | 2,375 | 5 | 173 | 1,011 | 224 |
| Diarrhoea | 2,247 | 5 | 235 | 831 | 125 |
| Fall | 2,164 | 4 | 107 | 1,456 | 129 |
| Drug resistance | 2,164 | 5 | 275 | 281 | 29 |
| Nausea | 2,081 | 5 | 114 | 998 | 81 |
| Fatigue | 2,065 | 4 | 154 | 698 | 88 |
| Drug reaction with eosinophilia and systemic symptoms | 1,922 | 5 | 103 | 1,285 | 253 |
| Pyrexia | 1,886 | 5 | 173 | 1,285 | 235 |
| Vomiting | 1,800 | 5 | 133 | 1,120 | 135 |
| Dizziness | 1,726 | 5 | 41 | 659 | 82 |
| Drug hypersensitivity | 1,637 | 5 | 53 | 236 | 40 |
| Pain | 1,542 | 4 | 51 | 908 | 137 |
| Hypotension | 1,537 | 5 | 122 | 1,149 | 279 |
| Maternal exposure during pregnancy | 1,527 | 5 | 70 | 224 | 53 |
| Condition aggravated | 1,484 | 5 | 175 | 758 | 170 |
| Somnolence | 1,375 | 5 | 58 | 608 | 87 |
| Dyspnoea | 1,316 | 4 | 226 | 757 | 209 |
| Headache | 1,313 | 4 | 55 | 518 | 67 |
| Exposure during pregnancy | 1,309 | 5 | 40 | 172 | 15 |
| Asthenia | 1,288 | 4 | 129 | 627 | 62 |
| Epilepsy | 1,283 | 5 | 59 | 412 | 56 |
| Balance disorder | 1,269 | 4 | 14 | 883 | 104 |