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Important: This site presents data from the FDA Adverse Event Reporting System (FAERS). A report does not mean the drug caused the event. Full disclaimer.

Cytochrome P450 2C9 Inducers [MoA]: Side Effects & Safety Data for 13 Drugs

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Cytochrome P450 2C9 Inducers [MoA] includes 13 drugs with a combined 154,086 adverse event reports in the FDA FAERS database. Compare their safety profiles, side effects, and outcomes below.

13
Drugs in Class
154,086
Combined Reports

All Cytochrome P450 2C9 Inducers [MoA] Drugs Ranked by Reports

Drug Brand Name Reports Deaths Hosp. Death Rate
ENZALUTAMIDE Xtandi 49,270 9,676 9,282 19.6%
CARBAMAZEPINE Carbamazepine 24,577 2,156 9,608 8.8%
BOSENTAN Tracleer 19,581 4,346 8,862 22.2%
DABRAFENIB Tafinlar 19,305 4,165 5,325 21.6%
PHENYTOIN PHENYTOIN SODIUM 14,469 1,449 5,241 10.0%
RITONAVIR Norvir 11,980 1,190 2,925 9.9%
APREPITANT CINVANTI 5,620 1,195 2,917 21.3%
SPARSENTAN FILSPARI 3,280 18 209 0.5%
IVOSIDENIB TIBSOVO 1,695 121 505 7.1%
LETERMOVIR PREVYMIS 1,416 252 398 17.8%
FOSPHENYTOIN CEREBYX 1,378 166 646 12.0%
FOSAPREPITANT DIMEGLUMINE Fosaprepitant 888 118 364 13.3%
MITAPIVAT PYRUKYND 627 4 58 0.6%

Common Side Effects in Cytochrome P450 2C9 Inducers [MoA] Drugs

Side EffectReportsDeaths
Fatigue 14,180 1,296
Death 13,090 13,067
Drug ineffective 11,217 1,044
Nausea 7,620 824
Pyrexia 7,443 990
Malignant neoplasm progression 6,474 2,219
Dizziness 6,287 632
Asthenia 6,198 914
Off label use 6,102 959
Dyspnoea 6,092 1,114
View detailed side effects for this class → Compare drugs in this class →