DNA Polymerase Inhibitors [MoA]: Side Effects & Safety Data for 8 Drugs
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DNA Polymerase Inhibitors [MoA] includes 8 drugs with a combined 43,558 adverse event reports in the FDA FAERS database. Compare their safety profiles, side effects, and outcomes below.
8
Drugs in Class
43,558
Combined Reports
All DNA Polymerase Inhibitors [MoA] Drugs Ranked by Reports
| Drug | Brand Name | Reports | Deaths | Hosp. | Death Rate |
|---|---|---|---|---|---|
| ACYCLOVIR | Acyclovir | 14,197 | 2,057 | 6,095 | 14.5% |
| VALACYCLOVIR | Valacyclovir Hydrochloride | 13,138 | 812 | 6,169 | 6.2% |
| VALGANCICLOVIR | VALGANCICLOVIR | 7,913 | 1,274 | 3,092 | 16.1% |
| GANCICLOVIR | Ganciclovir | 4,990 | 1,469 | 1,735 | 29.4% |
| FOSCARNET | Foscarnet Sodium | 2,057 | 605 | 608 | 29.4% |
| CIDOFOVIR | CIDOFOVIR | 715 | 165 | 238 | 23.1% |
| FAMCICLOVIR | Famciclovir | 495 | 30 | 162 | 6.1% |
| PENCICLOVIR | PENCICLOVIR | 53 | 2 | 1 | 3.8% |
Common Side Effects in DNA Polymerase Inhibitors [MoA] Drugs
| Side Effect | Reports | Deaths |
|---|---|---|
| Off label use | 5,352 | 1,393 |
| Drug ineffective | 5,062 | 1,441 |
| Acute kidney injury | 3,281 | 540 |
| Cytomegalovirus infection | 2,190 | 388 |
| Drug resistance | 2,042 | 348 |
| Neutropenia | 1,843 | 266 |
| Pyrexia | 1,660 | 294 |
| Product use in unapproved indication | 1,512 | 320 |
| Condition aggravated | 1,415 | 362 |
| Pancytopenia | 1,414 | 534 |