DNA Polymerase Inhibitors [MoA] — Common Side Effects
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| Side Effect | Total Reports | Drugs | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| Off label use | 5,352 | 7 | 1,393 | 1,908 | 375 |
| Drug ineffective | 5,062 | 8 | 1,441 | 1,899 | 519 |
| Acute kidney injury | 3,281 | 7 | 540 | 2,153 | 402 |
| Cytomegalovirus infection | 2,190 | 6 | 388 | 719 | 142 |
| Drug resistance | 2,042 | 7 | 348 | 504 | 140 |
| Neutropenia | 1,843 | 6 | 266 | 804 | 143 |
| Pyrexia | 1,660 | 7 | 294 | 1,019 | 159 |
| Product use in unapproved indication | 1,512 | 7 | 320 | 483 | 108 |
| Condition aggravated | 1,415 | 7 | 362 | 666 | 165 |
| Pancytopenia | 1,414 | 6 | 534 | 781 | 193 |
| Diarrhoea | 1,287 | 7 | 191 | 687 | 108 |
| Headache | 1,229 | 6 | 55 | 523 | 53 |
| Renal impairment | 1,227 | 7 | 204 | 616 | 130 |
| Thrombocytopenia | 1,216 | 6 | 297 | 716 | 155 |
| Pathogen resistance | 1,198 | 7 | 252 | 180 | 151 |
| Nausea | 1,177 | 7 | 56 | 514 | 43 |
| Rash | 1,096 | 6 | 121 | 467 | 78 |
| Leukopenia | 1,080 | 6 | 251 | 536 | 120 |
| Cytomegalovirus viraemia | 1,006 | 6 | 210 | 283 | 182 |
| Confusional state | 987 | 6 | 61 | 705 | 91 |
| Cytomegalovirus infection reactivation | 956 | 6 | 324 | 446 | 123 |
| Dyspnoea | 917 | 6 | 85 | 490 | 85 |
| Product use issue | 911 | 6 | 226 | 289 | 46 |
| Pneumonia | 880 | 7 | 308 | 499 | 123 |
| Neurotoxicity | 876 | 4 | 33 | 623 | 79 |
| Nephropathy toxic | 876 | 6 | 271 | 460 | 36 |
| Death | 867 | 5 | 864 | 149 | 60 |
| Vomiting | 839 | 7 | 47 | 507 | 52 |
| Renal failure | 831 | 6 | 217 | 474 | 129 |
| Multiple organ dysfunction syndrome | 808 | 6 | 716 | 331 | 199 |