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Important: This site presents data from the FDA Adverse Event Reporting System (FAERS). A report does not mean the drug caused the event. Full disclaimer.

Endothelin Receptor Antagonist [EPC]: Side Effects & Safety Data for 5 Drugs

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Endothelin Receptor Antagonist [EPC] includes 5 drugs with a combined 154,393 adverse event reports in the FDA FAERS database. Compare their safety profiles, side effects, and outcomes below.

5
Drugs in Class
154,393
Combined Reports

All Endothelin Receptor Antagonist [EPC] Drugs Ranked by Reports

Drug Brand Name Reports Deaths Hosp. Death Rate
AMBRISENTAN AMBRISENTAN 86,197 10,291 32,910 11.9%
MACITENTAN OPSYNVI 45,325 9,886 24,183 21.8%
BOSENTAN Tracleer 19,581 4,346 8,862 22.2%
SPARSENTAN FILSPARI 3,280 18 209 0.5%
APROCITENTAN TRYVIO 10 0 3 N/A

Common Side Effects in Endothelin Receptor Antagonist [EPC] Drugs

Side EffectReportsDeaths
Dyspnoea 24,259 2,840
Death 15,760 15,626
Headache 13,329 872
Pneumonia 9,311 1,443
Fatigue 9,081 746
Diarrhoea 8,899 874
Dizziness 8,507 525
Nausea 8,445 708
Fluid retention 7,400 928
Malaise 7,318 775
View detailed side effects for this class → Compare drugs in this class →