Endothelin Receptor Antagonist [EPC] — Common Side Effects
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| Side Effect | Total Reports | Drugs | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| Dyspnoea | 24,259 | 4 | 2,840 | 13,774 | 394 |
| Death | 15,760 | 4 | 15,626 | 4,052 | 202 |
| Headache | 13,329 | 4 | 872 | 5,054 | 145 |
| Pneumonia | 9,311 | 4 | 1,443 | 7,927 | 201 |
| Fatigue | 9,081 | 4 | 746 | 3,689 | 107 |
| Diarrhoea | 8,899 | 4 | 874 | 4,271 | 136 |
| Dizziness | 8,507 | 4 | 525 | 3,337 | 86 |
| Nausea | 8,445 | 4 | 708 | 3,854 | 144 |
| Fluid retention | 7,400 | 4 | 928 | 4,832 | 111 |
| Malaise | 7,318 | 4 | 775 | 3,529 | 85 |
| Cough | 6,143 | 4 | 500 | 2,713 | 92 |
| Peripheral swelling | 5,960 | 4 | 502 | 2,529 | 47 |
| Hypotension | 5,606 | 4 | 851 | 3,243 | 153 |
| Hospitalisation | 5,418 | 4 | 652 | 5,265 | 43 |
| Oedema peripheral | 5,341 | 4 | 622 | 2,465 | 116 |
| Pulmonary arterial hypertension | 5,133 | 3 | 1,994 | 3,467 | 188 |
| Vomiting | 4,909 | 4 | 426 | 2,749 | 97 |
| Chest pain | 4,824 | 4 | 387 | 2,991 | 71 |
| Nasal congestion | 4,808 | 4 | 216 | 1,236 | 38 |
| Pain | 4,408 | 4 | 353 | 2,119 | 42 |
| Oedema | 4,363 | 4 | 452 | 2,080 | 74 |
| Fall | 4,236 | 4 | 634 | 2,902 | 73 |
| Pain in extremity | 4,175 | 4 | 314 | 1,799 | 51 |
| Asthenia | 4,041 | 4 | 579 | 2,321 | 58 |
| Condition aggravated | 4,023 | 4 | 988 | 2,494 | 163 |
| Oxygen saturation decreased | 3,893 | 3 | 615 | 2,714 | 120 |
| Dyspnoea exertional | 3,796 | 4 | 440 | 2,065 | 56 |
| Syncope | 3,630 | 4 | 402 | 2,110 | 88 |
| Anaemia | 3,539 | 4 | 475 | 2,282 | 158 |
| Pulmonary hypertension | 3,513 | 3 | 1,306 | 2,431 | 133 |