Ester Local Anesthetic [EPC] — Common Side Effects
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| Side Effect | Total Reports | Drugs | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| Toxic anterior segment syndrome | 36 | 1 | 0 | 0 | 0 |
| Drug ineffective | 31 | 2 | 0 | 1 | 0 |
| Eye pain | 27 | 2 | 0 | 1 | 0 |
| Drug hypersensitivity | 24 | 1 | 0 | 1 | 1 |
| Eye irritation | 22 | 1 | 0 | 0 | 0 |
| Aqueous fibrin | 19 | 1 | 0 | 0 | 0 |
| Inflammation | 16 | 1 | 0 | 0 | 0 |
| Corneal epithelium defect | 15 | 1 | 0 | 0 | 0 |
| Pain | 11 | 1 | 0 | 1 | 0 |
| Vision blurred | 10 | 1 | 0 | 0 | 0 |
| Eye infection | 9 | 1 | 0 | 2 | 0 |
| Conjunctivitis | 9 | 1 | 0 | 0 | 0 |
| Anaesthetic complication | 9 | 1 | 0 | 2 | 1 |
| Eye inflammation | 8 | 1 | 0 | 0 | 0 |
| Visual impairment | 7 | 1 | 0 | 0 | 0 |
| Product temperature excursion issue | 7 | 1 | 0 | 0 | 0 |
| Off label use | 7 | 1 | 0 | 1 | 1 |
| Maternal exposure during pregnancy | 7 | 1 | 0 | 6 | 6 |
| Maternal exposure during delivery | 7 | 1 | 0 | 2 | 2 |
| Headache | 7 | 1 | 0 | 0 | 0 |
| Dyspnoea | 7 | 1 | 0 | 1 | 1 |
| Toxicity to various agents | 6 | 1 | 0 | 0 | 0 |
| Seizure | 6 | 1 | 3 | 0 | 0 |
| Photophobia | 6 | 1 | 0 | 0 | 0 |
| Fatigue | 6 | 1 | 0 | 1 | 1 |
| Eye pruritus | 6 | 1 | 0 | 0 | 0 |
| Chest discomfort | 6 | 1 | 0 | 0 | 0 |
| Vitreous floaters | 5 | 1 | 0 | 0 | 0 |
| Urticaria | 5 | 1 | 0 | 0 | 1 |
| Type i hypersensitivity | 5 | 1 | 0 | 4 | 4 |