HER2/Neu/cerbB2 Antagonists [MoA]: Side Effects & Safety Data for 3 Drugs
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HER2/Neu/cerbB2 Antagonists [MoA] includes 3 drugs with a combined 68,555 adverse event reports in the FDA FAERS database. Compare their safety profiles, side effects, and outcomes below.
3
Drugs in Class
68,555
Combined Reports
All HER2/Neu/cerbB2 Antagonists [MoA] Drugs Ranked by Reports
| Drug | Brand Name | Reports | Deaths | Hosp. | Death Rate |
|---|---|---|---|---|---|
| TRASTUZUMAB | Trazimera | 46,537 | 5,564 | 13,839 | 12.0% |
| PERTUZUMAB | PERJETA | 21,995 | 2,161 | 7,803 | 9.8% |
| MARGETUXIMAB | MARGENZA | 23 | 2 | 18 | 8.7% |
Common Side Effects in HER2/Neu/cerbB2 Antagonists [MoA] Drugs
| Side Effect | Reports | Deaths |
|---|---|---|
| Diarrhoea | 8,339 | 796 |
| Off label use | 5,688 | 1,174 |
| Nausea | 5,168 | 605 |
| Fatigue | 5,089 | 693 |
| Myelosuppression | 3,863 | 13 |
| Disease progression | 3,591 | 1,090 |
| Vomiting | 3,340 | 393 |
| Death | 3,185 | 3,183 |
| Dyspnoea | 2,997 | 319 |
| Pyrexia | 2,812 | 278 |