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Important: This site presents data from the FDA Adverse Event Reporting System (FAERS). A report does not mean the drug caused the event. Full disclaimer.

Janus Kinase Inhibitor [EPC]: Side Effects & Safety Data for 5 Drugs

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Janus Kinase Inhibitor [EPC] includes 5 drugs with a combined 300,714 adverse event reports in the FDA FAERS database. Compare their safety profiles, side effects, and outcomes below.

5
Drugs in Class
300,714
Combined Reports

All Janus Kinase Inhibitor [EPC] Drugs Ranked by Reports

Drug Brand Name Reports Deaths Hosp. Death Rate
TOFACITINIB XELJANZ XR 155,647 7,847 21,976 5.0%
RUXOLITINIB OPZELURA 68,133 10,908 14,461 16.0%
UPADACITINIB Rinvoq 65,656 2,406 15,931 3.7%
BARICITINIB Olumiant 8,108 717 2,498 8.8%
ABROCITINIB CIBINQO 3,170 57 329 1.8%

Common Side Effects in Janus Kinase Inhibitor [EPC] Drugs

Side EffectReportsDeaths
Drug ineffective 36,486 1,697
Pain 28,105 1,900
Off label use 26,140 3,385
Fatigue 21,585 2,025
Arthralgia 20,862 1,624
Condition aggravated 18,910 1,659
Rheumatoid arthritis 15,330 1,775
Headache 15,207 1,496
Pain in extremity 12,344 1,099
Joint swelling 12,136 1,802
View detailed side effects for this class → Compare drugs in this class →