Does ACETAMINOPHEN\HYDROCODONE Cause Hepatotoxicity? 57 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 57 reports of Hepatotoxicity have been filed in association with ACETAMINOPHEN\HYDROCODONE. This represents 0.1% of all adverse event reports for ACETAMINOPHEN\HYDROCODONE.
57
Reports of Hepatotoxicity with ACETAMINOPHEN\HYDROCODONE
0.1%
of all ACETAMINOPHEN\HYDROCODONE reports
33
Deaths
32
Hospitalizations
How Dangerous Is Hepatotoxicity From ACETAMINOPHEN\HYDROCODONE?
Of the 57 reports, 33 (57.9%) resulted in death, 32 (56.1%) required hospitalization, and 1 (1.8%) were considered life-threatening.
Is Hepatotoxicity Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for ACETAMINOPHEN\HYDROCODONE. However, 57 reports have been filed with the FAERS database.
What Other Side Effects Does ACETAMINOPHEN\HYDROCODONE Cause?
Drug dependence (41,789)
Overdose (30,936)
Dependence (28,841)
Death (16,341)
Pain (14,958)
Emotional distress (13,878)
Toxicity to various agents (10,343)
Drug withdrawal syndrome (8,378)
Ill-defined disorder (6,159)
Drug withdrawal syndrome neonatal (5,340)
What Other Drugs Cause Hepatotoxicity?
METHOTREXATE (1,917)
ACETAMINOPHEN (1,557)
LEFLUNOMIDE (829)
HYDROXYCHLOROQUINE (715)
PREDNISONE (707)
RITUXIMAB (702)
ETANERCEPT (699)
ADALIMUMAB (674)
CYCLOPHOSPHAMIDE (632)
SULFASALAZINE (613)
Which ACETAMINOPHEN\HYDROCODONE Alternatives Have Lower Hepatotoxicity Risk?
ACETAMINOPHEN\HYDROCODONE vs ACETAMINOPHEN/HYDROCODONE
ACETAMINOPHEN\HYDROCODONE vs ACETAMINOPHEN\IBUPROFEN
ACETAMINOPHEN\HYDROCODONE vs ACETAMINOPHEN\METHOCARBAMOL
ACETAMINOPHEN\HYDROCODONE vs ACETAMINOPHEN\OPIUM
ACETAMINOPHEN\HYDROCODONE vs ACETAMINOPHEN\OXYCODONE