Does AMITRIPTYLINE Cause Hepatotoxicity? 66 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 66 reports of Hepatotoxicity have been filed in association with AMITRIPTYLINE (AMITRIPTYLINE HYDROCHLORIDE). This represents 0.3% of all adverse event reports for AMITRIPTYLINE.
66
Reports of Hepatotoxicity with AMITRIPTYLINE
0.3%
of all AMITRIPTYLINE reports
28
Deaths
40
Hospitalizations
How Dangerous Is Hepatotoxicity From AMITRIPTYLINE?
Of the 66 reports, 28 (42.4%) resulted in death, 40 (60.6%) required hospitalization, and 31 (47.0%) were considered life-threatening.
Is Hepatotoxicity Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for AMITRIPTYLINE. However, 66 reports have been filed with the FAERS database.
What Other Side Effects Does AMITRIPTYLINE Cause?
Toxicity to various agents (3,001)
Drug ineffective (2,344)
Completed suicide (1,678)
Off label use (1,588)
Pain (1,300)
Fall (1,216)
Hypotension (1,205)
Drug abuse (1,116)
Dizziness (1,041)
Constipation (1,035)
What Other Drugs Cause Hepatotoxicity?
METHOTREXATE (1,917)
ACETAMINOPHEN (1,557)
LEFLUNOMIDE (829)
HYDROXYCHLOROQUINE (715)
PREDNISONE (707)
RITUXIMAB (702)
ETANERCEPT (699)
ADALIMUMAB (674)
CYCLOPHOSPHAMIDE (632)
SULFASALAZINE (613)
Which AMITRIPTYLINE Alternatives Have Lower Hepatotoxicity Risk?
AMITRIPTYLINE vs AMITRIPTYLINE\PERPHENAZINE
AMITRIPTYLINE vs AMIVANTAMAB
AMITRIPTYLINE vs AMIVANTAMAB-VMJW
AMITRIPTYLINE vs AMLODIPINE
AMITRIPTYLINE vs AMLODIPINE BESILATE