Does ANAKINRA Cause Hepatotoxicity? 133 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 133 reports of Hepatotoxicity have been filed in association with ANAKINRA (Kineret). This represents 1.1% of all adverse event reports for ANAKINRA.
133
Reports of Hepatotoxicity with ANAKINRA
1.1%
of all ANAKINRA reports
1
Deaths
19
Hospitalizations
How Dangerous Is Hepatotoxicity From ANAKINRA?
Of the 133 reports, 1 (0.8%) resulted in death, 19 (14.3%) required hospitalization, and 1 (0.8%) were considered life-threatening.
Is Hepatotoxicity Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for ANAKINRA. However, 133 reports have been filed with the FAERS database.
What Other Side Effects Does ANAKINRA Cause?
Off label use (4,317)
Drug ineffective (3,368)
Pain (1,344)
Condition aggravated (1,339)
Rheumatoid arthritis (1,300)
Drug intolerance (946)
Joint swelling (921)
Injection site pain (879)
Product dose omission issue (864)
Arthralgia (850)
What Other Drugs Cause Hepatotoxicity?
METHOTREXATE (1,917)
ACETAMINOPHEN (1,557)
LEFLUNOMIDE (829)
HYDROXYCHLOROQUINE (715)
PREDNISONE (707)
RITUXIMAB (702)
ETANERCEPT (699)
ADALIMUMAB (674)
CYCLOPHOSPHAMIDE (632)
SULFASALAZINE (613)
Which ANAKINRA Alternatives Have Lower Hepatotoxicity Risk?
ANAKINRA vs ANAMORELIN
ANAKINRA vs ANASTROZOLE
ANAKINRA vs ANDEXANET ALFA
ANAKINRA vs ANDROGEL
ANAKINRA vs ANETHOLTRITHION