Does ASPARAGINASE Cause Hepatic failure? 24 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 24 reports of Hepatic failure have been filed in association with ASPARAGINASE (Rylaze). This represents 0.5% of all adverse event reports for ASPARAGINASE.
24
Reports of Hepatic failure with ASPARAGINASE
0.5%
of all ASPARAGINASE reports
12
Deaths
12
Hospitalizations
How Dangerous Is Hepatic failure From ASPARAGINASE?
Of the 24 reports, 12 (50.0%) resulted in death, 12 (50.0%) required hospitalization, and 1 (4.2%) were considered life-threatening.
Is Hepatic failure Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for ASPARAGINASE. However, 24 reports have been filed with the FAERS database.
What Other Side Effects Does ASPARAGINASE Cause?
Febrile neutropenia (557)
Neutropenia (322)
Bacterial infection (295)
Off label use (267)
Secondary immunodeficiency (233)
Viral infection (228)
Clostridium difficile colitis (213)
Pyrexia (204)
Sepsis (200)
Pneumonia (196)
What Other Drugs Cause Hepatic failure?
ACETAMINOPHEN (1,392)
RIBAVIRIN (888)
CYCLOPHOSPHAMIDE (629)
METHOTREXATE (598)
BEVACIZUMAB (558)
SOFOSBUVIR (525)
RITUXIMAB (513)
VINCRISTINE (468)
DOXORUBICIN (462)
PREDNISOLONE (425)
Which ASPARAGINASE Alternatives Have Lower Hepatic failure Risk?
ASPARAGINASE vs ASPARAGINASE ERWINIA CHRYSANTHEMI
ASPARAGINASE vs ASPARAGINASE ERWINIA CHRYSANTHEMI -RYWN
ASPARAGINASE vs ASPIRIN
ASPARAGINASE vs ASPIRIN DL-LYSINE
ASPARAGINASE vs ASPIRIN LYSINE