Does AVELUMAB Cause Hepatotoxicity? 19 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 19 reports of Hepatotoxicity have been filed in association with AVELUMAB (BAVENCIO). This represents 0.5% of all adverse event reports for AVELUMAB.
19
Reports of Hepatotoxicity with AVELUMAB
0.5%
of all AVELUMAB reports
1
Deaths
7
Hospitalizations
How Dangerous Is Hepatotoxicity From AVELUMAB?
Of the 19 reports, 1 (5.3%) resulted in death, 7 (36.8%) required hospitalization, and 1 (5.3%) were considered life-threatening.
Is Hepatotoxicity Listed in the Official Label?
Yes, Hepatotoxicity is listed as a known adverse reaction in the official FDA drug label for AVELUMAB.
What Other Side Effects Does AVELUMAB Cause?
Death (361)
Disease progression (355)
Off label use (200)
Diarrhoea (153)
Infusion related reaction (142)
Pyrexia (129)
Fatigue (124)
Neoplasm progression (119)
Dyspnoea (100)
Nausea (99)
What Other Drugs Cause Hepatotoxicity?
METHOTREXATE (1,917)
ACETAMINOPHEN (1,557)
LEFLUNOMIDE (829)
HYDROXYCHLOROQUINE (715)
PREDNISONE (707)
RITUXIMAB (702)
ETANERCEPT (699)
ADALIMUMAB (674)
CYCLOPHOSPHAMIDE (632)
SULFASALAZINE (613)
Which AVELUMAB Alternatives Have Lower Hepatotoxicity Risk?
AVELUMAB vs AVIBACTAM
AVELUMAB vs AVIBACTAM\CEFTAZIDIME
AVELUMAB vs AVOBENZONE\HOMOSALATE\OCTINOXATE\OCTISALATE\OCTOCRYLENE\OXYBENZONE\TITANIUM DIOXIDE\ZINC
AVELUMAB vs AVOBENZONE\HOMOSALATE\OCTINOXATE\OCTISALATE\OXYBENZONE
AVELUMAB vs AVOBENZONE\HOMOSALATE\OCTISALATE\OCTOCRYLENE