Does BEVACIZUMAB Cause Hepatotoxicity? 203 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 203 reports of Hepatotoxicity have been filed in association with BEVACIZUMAB (JOBEVNE). This represents 0.3% of all adverse event reports for BEVACIZUMAB.
203
Reports of Hepatotoxicity with BEVACIZUMAB
0.3%
of all BEVACIZUMAB reports
28
Deaths
30
Hospitalizations
How Dangerous Is Hepatotoxicity From BEVACIZUMAB?
Of the 203 reports, 28 (13.8%) resulted in death, 30 (14.8%) required hospitalization, and 3 (1.5%) were considered life-threatening.
Is Hepatotoxicity Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for BEVACIZUMAB. However, 203 reports have been filed with the FAERS database.
What Other Side Effects Does BEVACIZUMAB Cause?
Off label use (12,094)
Death (8,493)
Diarrhoea (4,911)
Disease progression (4,653)
Fatigue (4,572)
Nausea (4,357)
Hypertension (4,309)
Anaemia (3,221)
Vomiting (3,193)
Neutropenia (2,875)
What Other Drugs Cause Hepatotoxicity?
METHOTREXATE (1,917)
ACETAMINOPHEN (1,557)
LEFLUNOMIDE (829)
HYDROXYCHLOROQUINE (715)
PREDNISONE (707)
RITUXIMAB (702)
ETANERCEPT (699)
ADALIMUMAB (674)
CYCLOPHOSPHAMIDE (632)
SULFASALAZINE (613)
Which BEVACIZUMAB Alternatives Have Lower Hepatotoxicity Risk?
BEVACIZUMAB vs BEVACIZUMAB-AWWB
BEVACIZUMAB vs BEVACIZUMAB-BVZR
BEVACIZUMAB vs BEVACIZUMAB-MALY
BEVACIZUMAB vs BEXAROTENE
BEVACIZUMAB vs BEYAZ