Does BEVACIZUMAB Cause Intestinal perforation? 600 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 600 reports of Intestinal perforation have been filed in association with BEVACIZUMAB (JOBEVNE). This represents 0.8% of all adverse event reports for BEVACIZUMAB.
600
Reports of Intestinal perforation with BEVACIZUMAB
0.8%
of all BEVACIZUMAB reports
236
Deaths
239
Hospitalizations
How Dangerous Is Intestinal perforation From BEVACIZUMAB?
Of the 600 reports, 236 (39.3%) resulted in death, 239 (39.8%) required hospitalization, and 91 (15.2%) were considered life-threatening.
Is Intestinal perforation Listed in the Official Label?
Yes, Intestinal perforation is listed as a known adverse reaction in the official FDA drug label for BEVACIZUMAB.
What Other Side Effects Does BEVACIZUMAB Cause?
Off label use (12,094)
Death (8,493)
Diarrhoea (4,911)
Disease progression (4,653)
Fatigue (4,572)
Nausea (4,357)
Hypertension (4,309)
Anaemia (3,221)
Vomiting (3,193)
Neutropenia (2,875)
What Other Drugs Cause Intestinal perforation?
ADALIMUMAB (1,010)
RITUXIMAB (321)
TOCILIZUMAB (276)
PREDNISONE (266)
CYCLOPHOSPHAMIDE (262)
DOXORUBICIN (240)
LENVATINIB (228)
INFLIXIMAB (226)
PEMBROLIZUMAB (220)
METHOTREXATE (202)
Which BEVACIZUMAB Alternatives Have Lower Intestinal perforation Risk?
BEVACIZUMAB vs BEVACIZUMAB-AWWB
BEVACIZUMAB vs BEVACIZUMAB-BVZR
BEVACIZUMAB vs BEVACIZUMAB-MALY
BEVACIZUMAB vs BEXAROTENE
BEVACIZUMAB vs BEYAZ