Does CYCLOPHOSPHAMIDE Cause Intestinal perforation? 262 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 262 reports of Intestinal perforation have been filed in association with CYCLOPHOSPHAMIDE (Cyclophosphamide). This represents 0.2% of all adverse event reports for CYCLOPHOSPHAMIDE.
262
Reports of Intestinal perforation with CYCLOPHOSPHAMIDE
0.2%
of all CYCLOPHOSPHAMIDE reports
106
Deaths
148
Hospitalizations
How Dangerous Is Intestinal perforation From CYCLOPHOSPHAMIDE?
Of the 262 reports, 106 (40.5%) resulted in death, 148 (56.5%) required hospitalization, and 44 (16.8%) were considered life-threatening.
Is Intestinal perforation Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for CYCLOPHOSPHAMIDE. However, 262 reports have been filed with the FAERS database.
What Other Side Effects Does CYCLOPHOSPHAMIDE Cause?
Off label use (12,578)
Febrile neutropenia (11,318)
Drug ineffective (8,142)
Neutropenia (7,352)
Disease progression (7,100)
Pyrexia (6,126)
Product use in unapproved indication (5,750)
Thrombocytopenia (4,669)
Pneumonia (4,595)
Nausea (4,561)
What Other Drugs Cause Intestinal perforation?
ADALIMUMAB (1,010)
BEVACIZUMAB (600)
RITUXIMAB (321)
TOCILIZUMAB (276)
PREDNISONE (266)
DOXORUBICIN (240)
LENVATINIB (228)
INFLIXIMAB (226)
PEMBROLIZUMAB (220)
METHOTREXATE (202)
Which CYCLOPHOSPHAMIDE Alternatives Have Lower Intestinal perforation Risk?
CYCLOPHOSPHAMIDE vs CYCLOPHOSPHAMIDE FOR , USP
CYCLOPHOSPHAMIDE vs CYCLOPHOSPHAMIDE\DOXORUBICIN\PREDNISONE\RITUXIMAB\VINCRISTINE
CYCLOPHOSPHAMIDE vs CYCLOPHOSPHAMIDE\DOXORUBICIN\PREDNISONE\VINCRISTINE
CYCLOPHOSPHAMIDE vs CYCLOSERINE
CYCLOPHOSPHAMIDE vs CYCLOSPORINE