Does TOCILIZUMAB Cause Intestinal perforation? 276 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 276 reports of Intestinal perforation have been filed in association with TOCILIZUMAB (Tocilizumab-anoh). This represents 0.3% of all adverse event reports for TOCILIZUMAB.
276
Reports of Intestinal perforation with TOCILIZUMAB
0.3%
of all TOCILIZUMAB reports
29
Deaths
157
Hospitalizations
How Dangerous Is Intestinal perforation From TOCILIZUMAB?
Of the 276 reports, 29 (10.5%) resulted in death, 157 (56.9%) required hospitalization, and 38 (13.8%) were considered life-threatening.
Is Intestinal perforation Listed in the Official Label?
Yes, Intestinal perforation is listed as a known adverse reaction in the official FDA drug label for TOCILIZUMAB.
What Other Side Effects Does TOCILIZUMAB Cause?
Drug ineffective (32,342)
Rheumatoid arthritis (20,652)
Pain (18,384)
Off label use (18,256)
Arthralgia (15,536)
Joint swelling (14,831)
Fatigue (13,802)
Rash (12,327)
Drug intolerance (11,952)
Contraindicated product administered (11,547)
What Other Drugs Cause Intestinal perforation?
ADALIMUMAB (1,010)
BEVACIZUMAB (600)
RITUXIMAB (321)
PREDNISONE (266)
CYCLOPHOSPHAMIDE (262)
DOXORUBICIN (240)
LENVATINIB (228)
INFLIXIMAB (226)
PEMBROLIZUMAB (220)
METHOTREXATE (202)
Which TOCILIZUMAB Alternatives Have Lower Intestinal perforation Risk?
TOCILIZUMAB vs TOCILIZUMAB-AAZG
TOCILIZUMAB vs TOCOPHEROL
TOCILIZUMAB vs TOFACITINIB
TOCILIZUMAB vs TOFERSEN
TOCILIZUMAB vs TOLNAFTATE