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Important: This site presents data from the FDA Adverse Event Reporting System (FAERS). A report does not mean the drug caused the event. Full disclaimer.

All Drugs Associated with Intestinal perforation

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386 drugs have been associated with Intestinal perforation in FAERS reports.

Drug Reports Deaths Hosp. Life-Threat.
ADALIMUMAB 1,010 76 638 31
BEVACIZUMAB 600 236 239 91
RITUXIMAB 321 98 161 44
TOCILIZUMAB 276 29 157 38
PREDNISONE 266 76 147 26
CYCLOPHOSPHAMIDE 262 106 148 44
DOXORUBICIN 240 86 112 32
LENVATINIB 228 47 151 25
INFLIXIMAB 226 25 134 11
PEMBROLIZUMAB 220 55 126 33
METHOTREXATE 202 23 110 23
PACLITAXEL 191 102 99 41
VINCRISTINE 191 72 108 22
DEXAMETHASONE 179 60 121 42
CARBOPLATIN 175 84 79 36
FLUOROURACIL 175 54 78 34
OXALIPLATIN 166 51 66 31
IPILIMUMAB 157 69 103 32
NIVOLUMAB 157 68 86 35
METHYLPREDNISOLONE 153 26 99 29
PREDNISOLONE 150 62 100 14
VEDOLIZUMAB 150 13 113 3
IRINOTECAN 144 51 63 17
CAPECITABINE 132 40 71 18
UPADACITINIB 130 3 74 2
LENALIDOMIDE 107 42 64 17
ETOPOSIDE 104 47 58 18
TACROLIMUS 104 42 68 22
LEUCOVORIN 102 31 42 16
CISPLATIN 96 44 43 15
RISANKIZUMAB-RZAA 94 7 63 2
CALCIUM\DEXTROSE\MAGNESIUM\SODIUM\SODIUM 92 53 83 0
CARBIDOPA\LEVODOPA 92 34 69 4
TOFACITINIB 89 8 51 8
ETANERCEPT 80 10 50 4
USTEKINUMAB 76 3 47 4
CYTARABINE 75 30 46 9
AZATHIOPRINE 72 13 21 6
MYCOPHENOLATE MOFETIL 71 35 41 26
CLOZAPINE 63 19 49 9
DOCETAXEL 63 42 33 14
ACETAMINOPHEN 62 6 49 16
CYCLOSPORINE 60 18 34 9
SULFASALAZINE 59 1 20 10
ATEZOLIZUMAB 58 26 34 8
CABOZANTINIB S-MALATE 56 12 30 11
IBUPROFEN 55 10 18 11
MESALAMINE 55 15 26 2
GEMCITABINE 54 30 31 25
PANTOPRAZOLE 53 27 46 12
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