Does GEMCITABINE Cause Intestinal perforation? 54 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 54 reports of Intestinal perforation have been filed in association with GEMCITABINE (Gemcitabine). This represents 0.2% of all adverse event reports for GEMCITABINE.
54
Reports of Intestinal perforation with GEMCITABINE
0.2%
of all GEMCITABINE reports
30
Deaths
31
Hospitalizations
How Dangerous Is Intestinal perforation From GEMCITABINE?
Of the 54 reports, 30 (55.6%) resulted in death, 31 (57.4%) required hospitalization, and 25 (46.3%) were considered life-threatening.
Is Intestinal perforation Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for GEMCITABINE. However, 54 reports have been filed with the FAERS database.
What Other Side Effects Does GEMCITABINE Cause?
Off label use (3,319)
Disease progression (3,123)
Thrombocytopenia (2,320)
Drug ineffective (2,003)
Malignant neoplasm progression (1,962)
Neutropenia (1,892)
Anaemia (1,745)
Pyrexia (1,511)
Nausea (1,336)
Myelosuppression (1,197)
What Other Drugs Cause Intestinal perforation?
ADALIMUMAB (1,010)
BEVACIZUMAB (600)
RITUXIMAB (321)
TOCILIZUMAB (276)
PREDNISONE (266)
CYCLOPHOSPHAMIDE (262)
DOXORUBICIN (240)
LENVATINIB (228)
INFLIXIMAB (226)
PEMBROLIZUMAB (220)
Which GEMCITABINE Alternatives Have Lower Intestinal perforation Risk?
GEMCITABINE vs GEMCITABINE\GEMCITABINE
GEMCITABINE vs GEMFIBROZIL
GEMCITABINE vs GEMTUZUMAB OZOGAMICIN
GEMCITABINE vs GEMZAR
GEMCITABINE vs GENTAMICIN