Does RITUXIMAB Cause Intestinal perforation? 321 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 321 reports of Intestinal perforation have been filed in association with RITUXIMAB (Rituxan). This represents 0.2% of all adverse event reports for RITUXIMAB.
321
Reports of Intestinal perforation with RITUXIMAB
0.2%
of all RITUXIMAB reports
98
Deaths
161
Hospitalizations
How Dangerous Is Intestinal perforation From RITUXIMAB?
Of the 321 reports, 98 (30.5%) resulted in death, 161 (50.2%) required hospitalization, and 44 (13.7%) were considered life-threatening.
Is Intestinal perforation Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for RITUXIMAB. However, 321 reports have been filed with the FAERS database.
What Other Side Effects Does RITUXIMAB Cause?
Off label use (39,751)
Drug ineffective (32,186)
Rheumatoid arthritis (19,850)
Pain (16,675)
Fatigue (15,602)
Arthralgia (12,529)
Rash (12,102)
Drug intolerance (11,876)
Infusion related reaction (11,871)
Joint swelling (11,170)
What Other Drugs Cause Intestinal perforation?
ADALIMUMAB (1,010)
BEVACIZUMAB (600)
TOCILIZUMAB (276)
PREDNISONE (266)
CYCLOPHOSPHAMIDE (262)
DOXORUBICIN (240)
LENVATINIB (228)
INFLIXIMAB (226)
PEMBROLIZUMAB (220)
METHOTREXATE (202)
Which RITUXIMAB Alternatives Have Lower Intestinal perforation Risk?
RITUXIMAB vs RITUXIMAB-ABBS
RITUXIMAB vs RITUXIMAB-ARRX
RITUXIMAB vs RITUXIMAB-PVVR
RITUXIMAB vs RIVAROXABAN
RITUXIMAB vs RIVASTIGMINE