Does LEUCOVORIN Cause Intestinal perforation? 102 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 102 reports of Intestinal perforation have been filed in association with LEUCOVORIN (LEUCOVORIN CALCIUM). This represents 0.4% of all adverse event reports for LEUCOVORIN.
102
Reports of Intestinal perforation with LEUCOVORIN
0.4%
of all LEUCOVORIN reports
31
Deaths
42
Hospitalizations
How Dangerous Is Intestinal perforation From LEUCOVORIN?
Of the 102 reports, 31 (30.4%) resulted in death, 42 (41.2%) required hospitalization, and 16 (15.7%) were considered life-threatening.
Is Intestinal perforation Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for LEUCOVORIN. However, 102 reports have been filed with the FAERS database.
What Other Side Effects Does LEUCOVORIN Cause?
Diarrhoea (2,594)
Neutropenia (2,291)
Nausea (1,977)
Neuropathy peripheral (1,557)
Disease progression (1,456)
Fatigue (1,443)
Vomiting (1,441)
Off label use (1,390)
Thrombocytopenia (1,181)
Pyrexia (1,148)
What Other Drugs Cause Intestinal perforation?
ADALIMUMAB (1,010)
BEVACIZUMAB (600)
RITUXIMAB (321)
TOCILIZUMAB (276)
PREDNISONE (266)
CYCLOPHOSPHAMIDE (262)
DOXORUBICIN (240)
LENVATINIB (228)
INFLIXIMAB (226)
PEMBROLIZUMAB (220)
Which LEUCOVORIN Alternatives Have Lower Intestinal perforation Risk?
LEUCOVORIN vs LEUCOVORIN\LEUCOVORIN
LEUCOVORIN vs LEUPROLIDE
LEUCOVORIN vs LEVALBUTEROL
LEUCOVORIN vs LEVAMISOLE
LEUCOVORIN vs LEVAQUIN