Does ETOPOSIDE Cause Intestinal perforation? 104 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 104 reports of Intestinal perforation have been filed in association with ETOPOSIDE (Avopef). This represents 0.2% of all adverse event reports for ETOPOSIDE.
104
Reports of Intestinal perforation with ETOPOSIDE
0.2%
of all ETOPOSIDE reports
47
Deaths
58
Hospitalizations
How Dangerous Is Intestinal perforation From ETOPOSIDE?
Of the 104 reports, 47 (45.2%) resulted in death, 58 (55.8%) required hospitalization, and 18 (17.3%) were considered life-threatening.
Is Intestinal perforation Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for ETOPOSIDE. However, 104 reports have been filed with the FAERS database.
What Other Side Effects Does ETOPOSIDE Cause?
Off label use (6,495)
Febrile neutropenia (5,966)
Disease progression (3,776)
Drug ineffective (3,687)
Neutropenia (3,641)
Thrombocytopenia (3,085)
Product use in unapproved indication (2,774)
Anaemia (2,586)
Pyrexia (2,453)
Sepsis (2,211)
What Other Drugs Cause Intestinal perforation?
ADALIMUMAB (1,010)
BEVACIZUMAB (600)
RITUXIMAB (321)
TOCILIZUMAB (276)
PREDNISONE (266)
CYCLOPHOSPHAMIDE (262)
DOXORUBICIN (240)
LENVATINIB (228)
INFLIXIMAB (226)
PEMBROLIZUMAB (220)
Which ETOPOSIDE Alternatives Have Lower Intestinal perforation Risk?
ETOPOSIDE vs ETORICOXIB
ETOPOSIDE vs ETRASIMOD ARGININE
ETOPOSIDE vs ETRAVIRINE
ETOPOSIDE vs EUCALYPTOL\MENTHOL\METHYL SALICYLATE\THYMOL
ETOPOSIDE vs EVEROLIMUS