Does CYTARABINE Cause Intestinal perforation? 75 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 75 reports of Intestinal perforation have been filed in association with CYTARABINE (cytarabine). This represents 0.2% of all adverse event reports for CYTARABINE.
75
Reports of Intestinal perforation with CYTARABINE
0.2%
of all CYTARABINE reports
30
Deaths
46
Hospitalizations
How Dangerous Is Intestinal perforation From CYTARABINE?
Of the 75 reports, 30 (40.0%) resulted in death, 46 (61.3%) required hospitalization, and 9 (12.0%) were considered life-threatening.
Is Intestinal perforation Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for CYTARABINE. However, 75 reports have been filed with the FAERS database.
What Other Side Effects Does CYTARABINE Cause?
Febrile neutropenia (6,142)
Off label use (4,183)
Pyrexia (2,992)
Neutropenia (2,558)
Disease progression (2,352)
Drug ineffective (2,281)
Thrombocytopenia (2,148)
Sepsis (2,013)
Myelosuppression (1,869)
Product use in unapproved indication (1,619)
What Other Drugs Cause Intestinal perforation?
ADALIMUMAB (1,010)
BEVACIZUMAB (600)
RITUXIMAB (321)
TOCILIZUMAB (276)
PREDNISONE (266)
CYCLOPHOSPHAMIDE (262)
DOXORUBICIN (240)
LENVATINIB (228)
INFLIXIMAB (226)
PEMBROLIZUMAB (220)
Which CYTARABINE Alternatives Have Lower Intestinal perforation Risk?
CYTARABINE vs CYTARABINE\DAUNORUBICIN
CYTARABINE vs DABIGATRAN
CYTARABINE vs DABIGATRAN ETEXILATE
CYTARABINE vs DABRAFENIB
CYTARABINE vs DABRAFENIB\TRAMETINIB