Does UPADACITINIB Cause Intestinal perforation? 130 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 130 reports of Intestinal perforation have been filed in association with UPADACITINIB (Rinvoq). This represents 0.2% of all adverse event reports for UPADACITINIB.
130
Reports of Intestinal perforation with UPADACITINIB
0.2%
of all UPADACITINIB reports
3
Deaths
74
Hospitalizations
How Dangerous Is Intestinal perforation From UPADACITINIB?
Of the 130 reports, 3 (2.3%) resulted in death, 74 (56.9%) required hospitalization, and 2 (1.5%) were considered life-threatening.
Is Intestinal perforation Listed in the Official Label?
Yes, Intestinal perforation is listed as a known adverse reaction in the official FDA drug label for UPADACITINIB.
What Other Side Effects Does UPADACITINIB Cause?
Pain (4,444)
Arthralgia (3,815)
Drug ineffective (3,384)
Covid-19 (2,978)
Rheumatoid arthritis (2,730)
Pain in extremity (2,353)
Fatigue (2,153)
Fall (2,081)
Surgery (2,037)
Therapy interrupted (1,741)
What Other Drugs Cause Intestinal perforation?
ADALIMUMAB (1,010)
BEVACIZUMAB (600)
RITUXIMAB (321)
TOCILIZUMAB (276)
PREDNISONE (266)
CYCLOPHOSPHAMIDE (262)
DOXORUBICIN (240)
LENVATINIB (228)
INFLIXIMAB (226)
PEMBROLIZUMAB (220)
Which UPADACITINIB Alternatives Have Lower Intestinal perforation Risk?
UPADACITINIB vs URAPIDIL
UPADACITINIB vs UREA
UPADACITINIB vs URIDINE TRIACETATE
UPADACITINIB vs UROFOLLITROPIN
UPADACITINIB vs URSODIOL