Does VINCRISTINE Cause Intestinal perforation? 191 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 191 reports of Intestinal perforation have been filed in association with VINCRISTINE (VinCRIStine Sulfate). This represents 0.3% of all adverse event reports for VINCRISTINE.
191
Reports of Intestinal perforation with VINCRISTINE
0.3%
of all VINCRISTINE reports
72
Deaths
108
Hospitalizations
How Dangerous Is Intestinal perforation From VINCRISTINE?
Of the 191 reports, 72 (37.7%) resulted in death, 108 (56.5%) required hospitalization, and 22 (11.5%) were considered life-threatening.
Is Intestinal perforation Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for VINCRISTINE. However, 191 reports have been filed with the FAERS database.
What Other Side Effects Does VINCRISTINE Cause?
Febrile neutropenia (8,676)
Off label use (6,562)
Disease progression (5,252)
Neutropenia (4,982)
Drug ineffective (4,084)
Pyrexia (3,460)
Product use in unapproved indication (3,073)
Thrombocytopenia (2,940)
Sepsis (2,791)
Anaemia (2,603)
What Other Drugs Cause Intestinal perforation?
ADALIMUMAB (1,010)
BEVACIZUMAB (600)
RITUXIMAB (321)
TOCILIZUMAB (276)
PREDNISONE (266)
CYCLOPHOSPHAMIDE (262)
DOXORUBICIN (240)
LENVATINIB (228)
INFLIXIMAB (226)
PEMBROLIZUMAB (220)
Which VINCRISTINE Alternatives Have Lower Intestinal perforation Risk?
VINCRISTINE vs VINDESINE
VINCRISTINE vs VINORELBINE
VINCRISTINE vs VINORELBINE\VINORELBINE
VINCRISTINE vs VIREAD
VINCRISTINE vs VISIPAQUE