Does PACLITAXEL Cause Intestinal perforation? 191 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 191 reports of Intestinal perforation have been filed in association with PACLITAXEL (PACLITAXEL PACLITAXEL). This represents 0.3% of all adverse event reports for PACLITAXEL.
191
Reports of Intestinal perforation with PACLITAXEL
0.3%
of all PACLITAXEL reports
102
Deaths
99
Hospitalizations
How Dangerous Is Intestinal perforation From PACLITAXEL?
Of the 191 reports, 102 (53.4%) resulted in death, 99 (51.8%) required hospitalization, and 41 (21.5%) were considered life-threatening.
Is Intestinal perforation Listed in the Official Label?
Yes, Intestinal perforation is listed as a known adverse reaction in the official FDA drug label for PACLITAXEL.
What Other Side Effects Does PACLITAXEL Cause?
Neutropenia (4,553)
Nausea (4,521)
Dyspnoea (4,519)
Diarrhoea (4,289)
Off label use (4,075)
Anaemia (3,949)
Neuropathy peripheral (3,508)
Malignant neoplasm progression (3,484)
Fatigue (3,418)
Death (3,143)
What Other Drugs Cause Intestinal perforation?
ADALIMUMAB (1,010)
BEVACIZUMAB (600)
RITUXIMAB (321)
TOCILIZUMAB (276)
PREDNISONE (266)
CYCLOPHOSPHAMIDE (262)
DOXORUBICIN (240)
LENVATINIB (228)
INFLIXIMAB (226)
PEMBROLIZUMAB (220)
Which PACLITAXEL Alternatives Have Lower Intestinal perforation Risk?
PACLITAXEL vs PACRITINIB
PACLITAXEL vs PALBOCICLIB
PACLITAXEL vs PALIPERIDONE
PACLITAXEL vs PALIVIZUMAB
PACLITAXEL vs PALONOSETRON