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Important: This site presents data from the FDA Adverse Event Reporting System (FAERS). A report does not mean the drug caused the event. Full disclaimer.

Does TOFACITINIB Cause Intestinal perforation? 89 Reports in FDA Database

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According to the FDA Adverse Event Reporting System (FAERS), 89 reports of Intestinal perforation have been filed in association with TOFACITINIB (XELJANZ XR). This represents 0.1% of all adverse event reports for TOFACITINIB.

89
Reports of Intestinal perforation with TOFACITINIB
0.1%
of all TOFACITINIB reports
8
Deaths
51
Hospitalizations

How Dangerous Is Intestinal perforation From TOFACITINIB?

Of the 89 reports, 8 (9.0%) resulted in death, 51 (57.3%) required hospitalization, and 8 (9.0%) were considered life-threatening.

Is Intestinal perforation Listed in the Official Label?

Yes, Intestinal perforation is listed as a known adverse reaction in the official FDA drug label for TOFACITINIB.

What Other Side Effects Does TOFACITINIB Cause?

Drug ineffective (30,382) Pain (21,659) Condition aggravated (16,925) Arthralgia (15,640) Fatigue (13,551) Rheumatoid arthritis (12,277) Off label use (11,736) Headache (11,061) Joint swelling (10,686) Malaise (9,040)

What Other Drugs Cause Intestinal perforation?

ADALIMUMAB (1,010) BEVACIZUMAB (600) RITUXIMAB (321) TOCILIZUMAB (276) PREDNISONE (266) CYCLOPHOSPHAMIDE (262) DOXORUBICIN (240) LENVATINIB (228) INFLIXIMAB (226) PEMBROLIZUMAB (220)

Which TOFACITINIB Alternatives Have Lower Intestinal perforation Risk?

TOFACITINIB vs TOFERSEN TOFACITINIB vs TOLNAFTATE TOFACITINIB vs TOLODODEKIN ALFA TOFACITINIB vs TOLTERODINE TOFACITINIB vs TOLVAPTAN

Related Pages

TOFACITINIB Full Profile All Intestinal perforation Reports All Drugs Causing Intestinal perforation TOFACITINIB Demographics