Does IBUPROFEN Cause Intestinal perforation? 55 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 55 reports of Intestinal perforation have been filed in association with IBUPROFEN (equate ibuprofen). This represents 0.1% of all adverse event reports for IBUPROFEN.
55
Reports of Intestinal perforation with IBUPROFEN
0.1%
of all IBUPROFEN reports
10
Deaths
18
Hospitalizations
How Dangerous Is Intestinal perforation From IBUPROFEN?
Of the 55 reports, 10 (18.2%) resulted in death, 18 (32.7%) required hospitalization, and 11 (20.0%) were considered life-threatening.
Is Intestinal perforation Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for IBUPROFEN. However, 55 reports have been filed with the FAERS database.
What Other Side Effects Does IBUPROFEN Cause?
Drug ineffective (9,352)
Drug hypersensitivity (5,269)
Nausea (4,129)
Vomiting (4,116)
Acute kidney injury (3,639)
Product use in unapproved indication (3,596)
Toxicity to various agents (3,584)
Off label use (3,556)
Intentional overdose (3,185)
Headache (3,010)
What Other Drugs Cause Intestinal perforation?
ADALIMUMAB (1,010)
BEVACIZUMAB (600)
RITUXIMAB (321)
TOCILIZUMAB (276)
PREDNISONE (266)
CYCLOPHOSPHAMIDE (262)
DOXORUBICIN (240)
LENVATINIB (228)
INFLIXIMAB (226)
PEMBROLIZUMAB (220)
Which IBUPROFEN Alternatives Have Lower Intestinal perforation Risk?
IBUPROFEN vs IBUPROFEN LYSINE
IBUPROFEN vs IBUPROFEN UNKNOWN PRODUCT
IBUPROFEN vs IBUPROFEN\IBUPROFEN
IBUPROFEN vs IBUPROFEN\PHENYLEPHRINE
IBUPROFEN vs IBUPROFEN\PSEUDOEPHEDRINE