Does IPILIMUMAB Cause Intestinal perforation? 157 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 157 reports of Intestinal perforation have been filed in association with IPILIMUMAB (YERVOY). This represents 0.4% of all adverse event reports for IPILIMUMAB.
157
Reports of Intestinal perforation with IPILIMUMAB
0.4%
of all IPILIMUMAB reports
69
Deaths
103
Hospitalizations
How Dangerous Is Intestinal perforation From IPILIMUMAB?
Of the 157 reports, 69 (43.9%) resulted in death, 103 (65.6%) required hospitalization, and 32 (20.4%) were considered life-threatening.
Is Intestinal perforation Listed in the Official Label?
Yes, Intestinal perforation is listed as a known adverse reaction in the official FDA drug label for IPILIMUMAB.
What Other Side Effects Does IPILIMUMAB Cause?
Death (3,710)
Malignant neoplasm progression (3,296)
Diarrhoea (2,557)
Off label use (2,097)
Colitis (1,988)
Pyrexia (1,796)
Rash (1,556)
Fatigue (1,447)
Intentional product use issue (1,329)
Nausea (1,169)
What Other Drugs Cause Intestinal perforation?
ADALIMUMAB (1,010)
BEVACIZUMAB (600)
RITUXIMAB (321)
TOCILIZUMAB (276)
PREDNISONE (266)
CYCLOPHOSPHAMIDE (262)
DOXORUBICIN (240)
LENVATINIB (228)
INFLIXIMAB (226)
PEMBROLIZUMAB (220)
Which IPILIMUMAB Alternatives Have Lower Intestinal perforation Risk?
IPILIMUMAB vs IPRAGLIFLOZIN L-PROLINE
IPILIMUMAB vs IPRATROPIUM
IPILIMUMAB vs IPRATROPIUM\IPRATROPIUM ANHYDROUS
IPILIMUMAB vs IPTACOPAN
IPILIMUMAB vs IRBESARTAN