Does BORTEZOMIB Cause Hepatotoxicity? 124 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 124 reports of Hepatotoxicity have been filed in association with BORTEZOMIB (bortezomib). This represents 0.3% of all adverse event reports for BORTEZOMIB.
124
Reports of Hepatotoxicity with BORTEZOMIB
0.3%
of all BORTEZOMIB reports
12
Deaths
20
Hospitalizations
How Dangerous Is Hepatotoxicity From BORTEZOMIB?
Of the 124 reports, 12 (9.7%) resulted in death, 20 (16.1%) required hospitalization, and 6 (4.8%) were considered life-threatening.
Is Hepatotoxicity Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for BORTEZOMIB. However, 124 reports have been filed with the FAERS database.
What Other Side Effects Does BORTEZOMIB Cause?
Plasma cell myeloma (6,683)
Off label use (4,754)
Neuropathy peripheral (4,067)
Drug ineffective (2,730)
Diarrhoea (2,244)
Thrombocytopenia (2,082)
Death (2,025)
Pneumonia (2,020)
Fatigue (1,757)
Neutropenia (1,530)
What Other Drugs Cause Hepatotoxicity?
METHOTREXATE (1,917)
ACETAMINOPHEN (1,557)
LEFLUNOMIDE (829)
HYDROXYCHLOROQUINE (715)
PREDNISONE (707)
RITUXIMAB (702)
ETANERCEPT (699)
ADALIMUMAB (674)
CYCLOPHOSPHAMIDE (632)
SULFASALAZINE (613)
Which BORTEZOMIB Alternatives Have Lower Hepatotoxicity Risk?
BORTEZOMIB vs BOSENTAN
BORTEZOMIB vs BOSENTAN\BOSENTAN
BORTEZOMIB vs BOSULIF
BORTEZOMIB vs BOSUTINIB
BORTEZOMIB vs BOTOX