Does BRIGATINIB Cause Hepatotoxicity? 18 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 18 reports of Hepatotoxicity have been filed in association with BRIGATINIB (Alunbrig). This represents 0.6% of all adverse event reports for BRIGATINIB.
18
Reports of Hepatotoxicity with BRIGATINIB
0.6%
of all BRIGATINIB reports
0
Deaths
3
Hospitalizations
How Dangerous Is Hepatotoxicity From BRIGATINIB?
Of the 18 reports, 3 (16.7%) required hospitalization.
Is Hepatotoxicity Listed in the Official Label?
Yes, Hepatotoxicity is listed as a known adverse reaction in the official FDA drug label for BRIGATINIB.
What Other Side Effects Does BRIGATINIB Cause?
Death (405)
Non-small cell lung cancer (370)
Off label use (256)
Diarrhoea (239)
Metastases to central nervous system (219)
Nausea (218)
Lung neoplasm malignant (216)
Fatigue (201)
Blood creatine phosphokinase increased (198)
Product dose omission issue (193)
What Other Drugs Cause Hepatotoxicity?
METHOTREXATE (1,917)
ACETAMINOPHEN (1,557)
LEFLUNOMIDE (829)
HYDROXYCHLOROQUINE (715)
PREDNISONE (707)
RITUXIMAB (702)
ETANERCEPT (699)
ADALIMUMAB (674)
CYCLOPHOSPHAMIDE (632)
SULFASALAZINE (613)
Which BRIGATINIB Alternatives Have Lower Hepatotoxicity Risk?
BRIGATINIB vs BRILINTA
BRIGATINIB vs BRILIQUE
BRIGATINIB vs BRIMONIDINE
BRIGATINIB vs BRIMONIDINE\BRINZOLAMIDE
BRIGATINIB vs BRIMONIDINE\TIMOLOL