Does BUSULFAN Cause Cardiotoxicity? 56 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 56 reports of Cardiotoxicity have been filed in association with BUSULFAN (Busulfan). This represents 0.5% of all adverse event reports for BUSULFAN.
56
Reports of Cardiotoxicity with BUSULFAN
0.5%
of all BUSULFAN reports
14
Deaths
12
Hospitalizations
How Dangerous Is Cardiotoxicity From BUSULFAN?
Of the 56 reports, 14 (25.0%) resulted in death, 12 (21.4%) required hospitalization, and 2 (3.6%) were considered life-threatening.
Is Cardiotoxicity Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for BUSULFAN. However, 56 reports have been filed with the FAERS database.
What Other Side Effects Does BUSULFAN Cause?
Off label use (1,402)
Product use in unapproved indication (1,387)
Mucosal inflammation (880)
Venoocclusive liver disease (765)
Febrile neutropenia (628)
Cytomegalovirus infection (620)
Drug ineffective (569)
Graft versus host disease (507)
Pyrexia (502)
Cytomegalovirus infection reactivation (481)
What Other Drugs Cause Cardiotoxicity?
DOXORUBICIN (1,366)
CYCLOPHOSPHAMIDE (1,009)
TRASTUZUMAB (950)
VINCRISTINE (446)
FLUOROURACIL (425)
RITUXIMAB (389)
ETOPOSIDE (366)
CAPECITABINE (307)
TOCILIZUMAB (278)
PREDNISONE (277)
Which BUSULFAN Alternatives Have Lower Cardiotoxicity Risk?
BUSULFAN vs BUSULFEX
BUSULFAN vs BUTALBITAL
BUSULFAN vs BUTENAFINE
BUSULFAN vs BUTORPHANOL
BUSULFAN vs BUTRANS