Does CAPECITABINE Cause Hepatotoxicity? 254 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 254 reports of Hepatotoxicity have been filed in association with CAPECITABINE (Capecitabine). This represents 0.4% of all adverse event reports for CAPECITABINE.
254
Reports of Hepatotoxicity with CAPECITABINE
0.4%
of all CAPECITABINE reports
18
Deaths
45
Hospitalizations
How Dangerous Is Hepatotoxicity From CAPECITABINE?
Of the 254 reports, 18 (7.1%) resulted in death, 45 (17.7%) required hospitalization, and 8 (3.1%) were considered life-threatening.
Is Hepatotoxicity Listed in the Official Label?
Yes, Hepatotoxicity is listed as a known adverse reaction in the official FDA drug label for CAPECITABINE.
What Other Side Effects Does CAPECITABINE Cause?
Diarrhoea (9,277)
Nausea (6,248)
Palmar-plantar erythrodysaesthesia syndrome (5,294)
Fatigue (5,018)
Death (4,422)
Vomiting (4,111)
Disease progression (3,808)
Off label use (3,193)
Malignant neoplasm progression (2,425)
Asthenia (2,352)
What Other Drugs Cause Hepatotoxicity?
METHOTREXATE (1,917)
ACETAMINOPHEN (1,557)
LEFLUNOMIDE (829)
HYDROXYCHLOROQUINE (715)
PREDNISONE (707)
RITUXIMAB (702)
ETANERCEPT (699)
ADALIMUMAB (674)
CYCLOPHOSPHAMIDE (632)
SULFASALAZINE (613)
Which CAPECITABINE Alternatives Have Lower Hepatotoxicity Risk?
CAPECITABINE vs CAPIVASERTIB
CAPECITABINE vs CAPLACIZUMAB
CAPECITABINE vs CAPLACIZUMAB-YHDP
CAPECITABINE vs CAPMATINIB
CAPECITABINE vs CAPREOMYCIN