Does CLOFARABINE Cause Hepatotoxicity? 23 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 23 reports of Hepatotoxicity have been filed in association with CLOFARABINE (Clofarabine). This represents 1.6% of all adverse event reports for CLOFARABINE.
23
Reports of Hepatotoxicity with CLOFARABINE
1.6%
of all CLOFARABINE reports
7
Deaths
9
Hospitalizations
How Dangerous Is Hepatotoxicity From CLOFARABINE?
Of the 23 reports, 7 (30.4%) resulted in death, 9 (39.1%) required hospitalization.
Is Hepatotoxicity Listed in the Official Label?
Yes, Hepatotoxicity is listed as a known adverse reaction in the official FDA drug label for CLOFARABINE.
What Other Side Effects Does CLOFARABINE Cause?
Febrile neutropenia (201)
Off label use (158)
Drug ineffective (139)
Pyrexia (139)
Mucosal inflammation (89)
Sepsis (85)
Alanine aminotransferase increased (82)
Acute kidney injury (80)
Multiple organ dysfunction syndrome (77)
Aspartate aminotransferase increased (76)
What Other Drugs Cause Hepatotoxicity?
METHOTREXATE (1,917)
ACETAMINOPHEN (1,557)
LEFLUNOMIDE (829)
HYDROXYCHLOROQUINE (715)
PREDNISONE (707)
RITUXIMAB (702)
ETANERCEPT (699)
ADALIMUMAB (674)
CYCLOPHOSPHAMIDE (632)
SULFASALAZINE (613)
Which CLOFARABINE Alternatives Have Lower Hepatotoxicity Risk?
CLOFARABINE vs CLOFAZIMINE
CLOFARABINE vs CLOMETHIAZOLE
CLOFARABINE vs CLOMIPHENE
CLOFARABINE vs CLOMIPRAMINE
CLOFARABINE vs CLONAZEPAM