Does CYTARABINE Cause Hepatotoxicity? 366 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 366 reports of Hepatotoxicity have been filed in association with CYTARABINE (cytarabine). This represents 0.8% of all adverse event reports for CYTARABINE.
366
Reports of Hepatotoxicity with CYTARABINE
0.8%
of all CYTARABINE reports
73
Deaths
91
Hospitalizations
How Dangerous Is Hepatotoxicity From CYTARABINE?
Of the 366 reports, 73 (19.9%) resulted in death, 91 (24.9%) required hospitalization, and 49 (13.4%) were considered life-threatening.
Is Hepatotoxicity Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for CYTARABINE. However, 366 reports have been filed with the FAERS database.
What Other Side Effects Does CYTARABINE Cause?
Febrile neutropenia (6,142)
Off label use (4,183)
Pyrexia (2,992)
Neutropenia (2,558)
Disease progression (2,352)
Drug ineffective (2,281)
Thrombocytopenia (2,148)
Sepsis (2,013)
Myelosuppression (1,869)
Product use in unapproved indication (1,619)
What Other Drugs Cause Hepatotoxicity?
METHOTREXATE (1,917)
ACETAMINOPHEN (1,557)
LEFLUNOMIDE (829)
HYDROXYCHLOROQUINE (715)
PREDNISONE (707)
RITUXIMAB (702)
ETANERCEPT (699)
ADALIMUMAB (674)
CYCLOPHOSPHAMIDE (632)
SULFASALAZINE (613)
Which CYTARABINE Alternatives Have Lower Hepatotoxicity Risk?
CYTARABINE vs CYTARABINE\DAUNORUBICIN
CYTARABINE vs DABIGATRAN
CYTARABINE vs DABIGATRAN ETEXILATE
CYTARABINE vs DABRAFENIB
CYTARABINE vs DABRAFENIB\TRAMETINIB