Does DANTROLENE Cause Hepatotoxicity? 7 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 7 reports of Hepatotoxicity have been filed in association with DANTROLENE (Dantrolene Sodium). This represents 2.4% of all adverse event reports for DANTROLENE.
7
Reports of Hepatotoxicity with DANTROLENE
2.4%
of all DANTROLENE reports
1
Deaths
0
Hospitalizations
How Dangerous Is Hepatotoxicity From DANTROLENE?
Of the 7 reports, 1 (14.3%) resulted in death.
Is Hepatotoxicity Listed in the Official Label?
Yes, Hepatotoxicity is listed as a known adverse reaction in the official FDA drug label for DANTROLENE.
What Other Side Effects Does DANTROLENE Cause?
Drug ineffective (74)
Neuroleptic malignant syndrome (50)
Off label use (30)
Respiratory failure (20)
Drug ineffective for unapproved indication (18)
Nausea (17)
Dizziness (15)
Pyrexia (15)
Asthenia (14)
Decreased appetite (14)
What Other Drugs Cause Hepatotoxicity?
METHOTREXATE (1,917)
ACETAMINOPHEN (1,557)
LEFLUNOMIDE (829)
HYDROXYCHLOROQUINE (715)
PREDNISONE (707)
RITUXIMAB (702)
ETANERCEPT (699)
ADALIMUMAB (674)
CYCLOPHOSPHAMIDE (632)
SULFASALAZINE (613)
Which DANTROLENE Alternatives Have Lower Hepatotoxicity Risk?
DANTROLENE vs DAPAGLIFLOZIN
DANTROLENE vs DAPAGLIFLOZIN PROPANEDIOL
DANTROLENE vs DAPAGLIFLOZIN PROPANEDIOL\METFORMIN
DANTROLENE vs DAPRODUSTAT
DANTROLENE vs DAPSONE