Does DAPSONE Cause Agranulocytosis? 21 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 21 reports of Agranulocytosis have been filed in association with DAPSONE (Dapsone). This represents 0.6% of all adverse event reports for DAPSONE.
21
Reports of Agranulocytosis with DAPSONE
0.6%
of all DAPSONE reports
1
Deaths
15
Hospitalizations
How Dangerous Is Agranulocytosis From DAPSONE?
Of the 21 reports, 1 (4.8%) resulted in death, 15 (71.4%) required hospitalization, and 8 (38.1%) were considered life-threatening.
Is Agranulocytosis Listed in the Official Label?
Yes, Agranulocytosis is listed as a known adverse reaction in the official FDA drug label for DAPSONE.
What Other Side Effects Does DAPSONE Cause?
Drug ineffective (673)
Off label use (506)
Drug reaction with eosinophilia and systemic symptoms (345)
Methaemoglobinaemia (322)
Treatment failure (260)
Product use in unapproved indication (168)
Condition aggravated (166)
Pyrexia (156)
Drug ineffective for unapproved indication (134)
Anaemia (117)
What Other Drugs Cause Agranulocytosis?
CLOZAPINE (1,766)
CYCLOPHOSPHAMIDE (1,242)
RITUXIMAB (1,154)
SULFAMETHOXAZOLE\TRIMETHOPRIM (797)
PANTOPRAZOLE (599)
METHOTREXATE (550)
SODIUM (549)
EPIRUBICIN (491)
METAMIZOLE (438)
DOCETAXEL (436)
Which DAPSONE Alternatives Have Lower Agranulocytosis Risk?
DAPSONE vs DAPTOMYCIN
DAPSONE vs DARATUMUMAB
DAPSONE vs DARATUMUMAB\HYALURONIDASE-FIHJ
DAPSONE vs DARBEPOETIN ALFA
DAPSONE vs DARIDOREXANT